Bacteria for Butanol Production: Bottlenecks, Achievements and Prospects

Grid Computing Achievements and Prospects

gCube Information Retrieval Engine differentiates from federated search. Data and services are scattered over the infrastructure instead of being contained in confined sub-sections, made accessible via narrow interfaces. Grid, where gCube runs, is not meant for interactive work, but offers a vast pool of resources for processing large amounts of information. In such domain it comes as natural c...

Engineering alternative butanol production platforms in heterologous bacteria.

Alternative microbial hosts have been engineered as biocatalysts for butanol biosynthesis. The butanol synthetic pathway of Clostridium acetobutylicum was first re-constructed in Escherichia coli to establish a baseline for comparison to other hosts. Whereas polycistronic expression of the pathway genes resulted in the production of 34 mg/L butanol, individual expression of pathway genes elevat...

Engineering Alternative Butanol Production Platforms in 1 Heterologous Bacteria

Synthetic Melatoninergic Ligands: Achievements and Prospects

Pineal hormone melatonin is widely used in the treatment of disorders of circadian rhythms. The presence of melatonin receptors in various animal tissues motivates the use of this hormone in some other diseases. For this reason, in recent years investigators continued the search for synthetic analogues of melatonin which are metabolically stable and selective to receptors. This review includes ...

Medical biotechnology: Achievements, prospects and perceptions